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Search Results for " coronary artery disease "

20

Compounds

Cat No. Product Name Synonyms Targets
TN6715 7-Ketocholesterol Others
7-Ketocholesterol is a metabolite of Cholesterol
T9023 Atuliflapon AZD5718 FLAP
Atuliflapon (AZD5718) is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
T6033 Zotarolimus ABT-578,A 179578 mTOR
Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
T0154 Nebivolol hydrochloride R 065824 hydrochloride,Nebivolol HCl,R-65824 Apoptosis , Adrenergic Receptor
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...
T1986 Atopaxar E5555,ER-172594-00 Protease-activated Receptor
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T19345 GP2-114 Others
GP2-114 is a catecholamine exercise mimetic that can be used to study coronary artery disease (CAD).
T8687 Diaminohydroxypropanetetraacetic acid Others
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others
T1986L Atopaxar Hydrobromide Protease-activated Receptor
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T2480 Apabetalone RVX-208,RVX000222 Epigenetic Reader Domain , HIV Protease
Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease.
T32155 Indecainide Ricainide,Ricainid,Decabid,Indecainidum,Indecainida Others
Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy.
T10364 Arbutamine GP 21213 Adrenergic Receptor
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be u...
T4179 Probucol disuccinate LDL
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
T61028 Mitiperstat AZD4831 Glutathione Peroxidase
Mitiperstat is a potent myeloperoxidase (MPO) inhibitor that is effective in preventing cardiovascular diseases such as heart failure and coronary artery disease.
T4287 Succinobucol Probucol monosuccinate,AGI-1067 Antioxidant , Reactive Oxygen Species
Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ...
T0182L2 (±) Clopidogrel hydrogen sulfate Plavix,Clopidogrel hydrogen sulfate,Iscover P2Y Receptor
(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph...
T31992 Granotapide CETP
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...
S00015 Tea polyphenol Apoptosis , Others , Autophagy
Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing c...
T73695 Canakinumab ACZ 885,Ilaris IL Receptor
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody.Canakinumab has been shown to inhibit human and chorioallantoic monkey IL-1β, with IC50 values of 43.6 and 40.8 pM, respectively.Canakinumab...
T14390L (2R,3S)-Azelaprag Apelin receptor
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...
T26739 Batifiban
Batifiban, a glycoprotein IIb/IIIa antagonist, is used potentially for the treatment of coronary artery disease.
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TargetMol